Sham Biology

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Sham surgery controls are

Debate continues about the ethics of sham surgery controls. The most powerful argument for sham surgery controls is that rigorous experiments are needed to demonstrate safety and efficacy of surgical procedures. Without such experiments, there is danger of adopting worthless procedures in clinical practice. Opponents of sham surgery controls argue that sham surgery constitutes unacceptable viol...

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Non-penetrating Sham Acupuncture

Most randomised-controlled trials of acupuncture use penetrating sham acupuncture as control intervention. Sham acupuncture is described as acupuncture at points which are not known as acupuncture points. Because of physiological changes due to skin penetration sham acupuncture should not be defined as placebo control. In 1998 a new placebo needle was introduced by Streitberger. This placebo ne...

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Sham Feeding? Same Feeding?

accepted, more obvious evidence is needed. In PPI, return of colonic motility is a hindmost concern; it takes 48 to 72 hours. Sham feeding enhances gastric emptying and increases rectosigmoid pressure activity. However, the influence of gum chewing on colonic motility is not clear. Alvimopan, a peripherally-acting μ-opioid receptor antagonist, was recently approved for the reduction of PPI afte...

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A "glyconutrient sham".

The discipline of glycobiology contributes to our understanding of human health and disease through research, most of which is published in peer-reviewed scientific journals. Recently, legitimate discoveries in glycobiology have been used as marketing tools to help sell plant extracts termed "glyconutrients." The glyconutrient industry has a worldwide sales force of over half a million people a...

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Sham TMS – A New Approach

Discussion: Sham TMS is a tradeoff between competing quality criteria. So far, the applied sham conditions accepted a reduced cortex stimulation effect to imitate the sensations of verum stimulation. We here focused on the development of a sham condition with only minor cortex stimulation. This was achieved by using a mu-metal shield between a double-coil arrangement. With two coils of the same...

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ژورنال

عنوان ژورنال: Science

سال: 1893

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.ns-21.538.287